Filling a Critical Knowledge Gap: Antiobesity Medications and Breastfeeding

In recent years, medications such as semaglutide and tirzepatide have transformed the treatment of obesity. These drugs, known as GLP-1–based therapies, have helped millions of adults achieve significant weight loss and improve cardiometabolic health. Yet, as their use has rapidly increased, particularly among women, an urgent question has emerged: Are these medications safe during breastfeeding? […]

Improving Diagnosis and Care for Childhood Urinary Tract Infections

Urinary tract infections (UTIs) are among the most common bacterial infections in infants and young children. When a child develops symptoms such as fever, clinicians must determine whether and how to evaluate for a UTI and decide on appropriate management. Despite how frequently these infections occur, important questions remain about how UTIs should be diagnosed […]

Nose swabs reveal bacteria that cause ear infections, helping to target treatments

• Amoxicillin is the right medication for more than 94 percent of children with ear infections. • A rapid nasal diagnostic test may reduce unnecessary antibiotic use while individualizing care for ear infections. • COVID-19 infections can occur at the same time as ear infections. Dr. Holly Frost often wondered if the antibiotics she prescribed […]

Study targets accurate diagnose, treatment of rare childhood eye cancer

In 2006, Dr. David Abramson helped introduce a way to treat childhood retinoblastomas by precisely injecting a small amount of a high-concentration chemotherapy directly to the eye’s single blood vessel. Retinoblastoma is an eye cancer that begins in the retina — the sensitive lining on the inside of the eye. A rare form of eye […]

Promising tool could make food allergy tests safer

Food allergies affect nearly 10 percent of children in the United States and seem to be growing more common. Now a researcher at the University of Michigan is testing a novel way to detect whether children might develop anaphylaxis during the oral food challenges conducted to diagnose food allergies. Dr. Charles Schuler, an expert in […]